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Invitrogen
CSP alpha Polyclonal Antibody
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CSP alpha Antibody (PA1-776) in WB
Western blot analysis of Cysteine String Protein alpha was performed using whole cell lysates of SH-SY5Y (Lane 1) and NIH/3T3 (Lane 2). The blots were probed with Anti- Cysteine String Protein alpha Rabbit polyclonal Antibody (Product # PA1-776, 2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). Bands of ~ 35 and 26 kDa, corresponding to mature and immature forms of Cysteine String Protein alpha respectively, were... View More
产品信息
PA1-776
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues E(180) T T Q L T A D S H P S Y H T D G F N(198) of rat CSP.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-776 detects Cysteine String Protein Alpha in mouse and rat brain samples.
PA1-776 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~34 kDa protein representing Cysteine String Protein Alpha in rat and mouse brain homogenates.
The PA1-776 immunogen is a synthetic peptide corresponding to residues E(180) T T Q L T A D S H P S Y H T D G F N(198) of rat CSP. This sequence is conserved across many species including mouse, human and bovine. This peptide (Cat. # PEP-287) is available for use in neutralization and control experiments.
靶标信息
Cysteine string protein alpha (CSPalpha) is a synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 chaperones. Cysteine-string proteins are membrane-bound proteins associated primarily with nerve endings and synaptic vesicles in the brain. These proteins play an important role in presynaptic function and may be involved in calcium-dependent neurotransmitter release. CSP proteins may act as presynaptic chaperones that assist in maintaining synaptic function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Ceroid-lipofuscinosis neuronal protein 4; CSP; CSP alpha; Cysteine string protein; cysteine string protein alpha; Cysteine-string protein isoform alpha; DnaJ (Hsp40) homolog, subfamily C, member 5; DnaJ homolog subfamily C member 5
基因别名: 2610314I24Rik; AU018536; CLN4; CLN4B; CSP; Cspalpha; DNAJC5; DNAJC5A; mir-941-2; mir-941-3; mir-941-4; mir-941-5; NCL
UniProt ID: (Human) Q9H3Z4, (Rat) P60905, (Mouse) P60904
Entrez Gene ID: (Human) 80331, (Rat) 79130, (Mouse) 13002
