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Invitrogen
Carbonic Anhydrase II Polyclonal Antibody
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Carbonic Anhydrase II Antibody (PA5-78897) in IHC (P)
Immunohistochemistry analysis of Carbonic Anhydrase II on paraffin-embedded human gastric cancer tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with Carbonic Anhydrase II polyclonal antibody (Product# PA5-78897) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-... View More
产品信息
PA5-78897
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human CA2 recombinant protein (Position: S2-K260).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human 293T whole cell, human THP-1 whole cell, human HEL whole cell, rat kidney tissue, rat stomach tissue, mouse kidney tissue, mouse stomach tissue. IHC: human gastric cancer tissue, human liver cancer tissue. Flow: HT-29 cell, SW480 cell.
靶标信息
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CA II; CA-II; CAC; Carbonate dehydratase II; Carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; carbonic dehydratase; Cyanamide hydratase CA2; epididymis luminal protein 76; epididymis secretory protein Li 282
基因别名: AI131712; CA-II; CA2; CAC; CAII; Car-2; Car2; HEL-76; HEL-S-282; Ltw-5; Lvtw-5
UniProt ID: (Human) P00918, (Mouse) P00920, (Rat) P27139
Entrez Gene ID: (Human) 760, (Mouse) 12349, (Rat) 54231
morphogenesis of an epithelium
one-carbon metabolic process
regulation of pH
carbon dioxide transport
positive regulation of synaptic transmission, GABAergic
positive regulation of cellular pH reduction
angiotensin-activated signaling pathway
regulation of anion transport
positive regulation of osteoclast differentiation
positive regulation of bone resorption
secretion
regulation of intracellular pH
positive regulation of dipeptide transmembrane transport
regulation of chloride transport
kidney development
response to pH
response to zinc ion
bicarbonate transport
odontogenesis of dentin-containing tooth
response to estrogen
response to steroid hormone
cellular response to fluid shear stress
response to organic substance
osteoclast differentiation
regulation of cellular pH
regulation of bone resorption
