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Invitrogen
Carbonic Anhydrase IV Recombinant Rabbit Monoclonal Antibody (039)
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Carbonic Anhydrase IV Antibody (MA5-29073) in IHC (P)
Immunohistochemical staining of human Carbonic Anhydrase IV in human lung with Carbonic Anhydrase IV Recombinant Rabbit Monoclonal Antibody (39) (Product # MA5-29073, 1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to pulmonary capillaries.
产品信息
MA5-29073
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
039
抗原
Recombinant Human Carbonic Anhydrase IV/CA4 protein (Met1-Lys283)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human Carbonic Anhydrase IV/CA4.
靶标信息
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CA-IV; Carbonate dehydratase IV; Carbonic anhydrase 4; Carbonic anhydrase IV; carbonic dehydratase IV
基因别名: CA4; CAIV; Car4; RP17
UniProt ID: (Human) P22748
Entrez Gene ID: (Human) 762
