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Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. The human CA5A gene encodes for the CA V protein which is expressed in the mitochondrial matrix in liver tissues, but can also be detected in many other tissues. In ureagenesis, the CA V protein may be involved in providing bicarbonate to carbamoyl phosphate synthetase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CA Y; CA-VA; Carbonate dehydratase VA; carbonic anhydrase 5 mitochondrial; carbonic anhydrase 5, mitochondrial; Carbonic anhydrase 5A, mitochondrial; carbonic anhydrase 5b, mitochondrial; Carbonic anhydrase VA; carbonic anhydrase Va, mitochondrial
基因别名: Ca5; Ca5a; Car5; Car5a; CAV
UniProt ID: (Rat) P43165, (Mouse) P23589
Entrez Gene ID: (Rat) 54233, (Mouse) 12352