Product References
CircRANBP17 modulated KDM1A to regulate neuroblastoma progression by sponging miR-27b-3p.
Open medicine (Warsaw, Poland)
Zhao L,Fan J,Zhang C,Zhang Z,Dong J
Published figure using Caspase 3 (Cleaved Asp175) polyclonal antibody (Product # PA5-114687) in Western Blot
Wed Mar 22 00:00:00 EDT 2023
miR-340-5p inhibits pancreatic acinar cell inflammation and apoptosis via targeted inhibition of HMGB1.
Experimental and therapeutic medicine
Gao Y,Wang L,Niu Z,Feng H,Liu J,Sun J,Gao Y,Pan L
PA5-114687 was used in Western Blot to present that miR-340-5p may be a useful strategy in AP via upregulation of HMGB1 and subsequent promotion of inflammation and apoptosis.
Tue Feb 01 00:00:00 EST 2022
Purine nucleoside phosphorylase deficiency induces p53-mediated intrinsic apoptosis in human induced pluripotent stem cell-derived neurons.
Scientific reports
Tsui M,Biro J,Chan J,Min W,Dobbs K,Notarangelo LD,Grunebaum E
PA5-114687 was used in Immunocytochemistry-immunoflourescence to establish a potential mechanism for the neurological defects observed in PNP-deficient patients and reinforce the critical role that PNP has for neuronal viability.
Tue May 31 00:00:00 EDT 2022
Purine nucleoside phosphorylase deficiency induces p53-mediated intrinsic apoptosis in human induced pluripotent stem cell-derived neurons.
Scientific reports
Tsui M,Biro J,Chan J,Min W,Dobbs K,Notarangelo LD,Grunebaum E
PA5-114687 was used in Immunocytochemistry-immunoflourescence to establish a potential mechanism for the neurological defects observed in PNP-deficient patients and reinforce the critical role that PNP has for neuronal viability.
Tue May 31 00:00:00 EDT 2022
Penta-O-Galloyl-β-D-Glucose in Pistacia integerrima Targets AMPK-ULK1 and ERK/STAT3 Signaling Axes to Induce ROS-Independent Autophagic Cell Death in Human Lung Cancer Cells.
Frontiers in pharmacology
Balkrishna A,Mulay VP,Verma S,Srivastava J,Lochab S,Varshney A
PA5-114687 was used in Western Blotting to propose PGG as a potential AMPK activator and STAT3 inhibitor that can be exploited further in developing adjuvant chemotherapeutics against lung cancer.
Sat Aug 06 00:00:00 EDT 2022
Penta-O-Galloyl-β-D-Glucose in Pistacia integerrima Targets AMPK-ULK1 and ERK/STAT3 Signaling Axes to Induce ROS-Independent Autophagic Cell Death in Human Lung Cancer Cells.
Frontiers in pharmacology
Balkrishna A,Mulay VP,Verma S,Srivastava J,Lochab S,Varshney A
PA5-114687 was used in Western Blotting to propose PGG as a potential AMPK activator and STAT3 inhibitor that can be exploited further in developing adjuvant chemotherapeutics against lung cancer.
Sat Aug 06 00:00:00 EDT 2022
Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.
Frontiers in pharmacology
Liang M,Zhu X,Zhang D,He W,Zhang J,Yuan S,He Q,Jin J
Published figure using Caspase 3 (Cleaved Asp175) polyclonal antibody (Product # PA5-114687) in Immunohistochemistry
Wed Dec 21 00:00:00 EST 2022
Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA5-Dependent Signaling.
Cellular and molecular gastroenterology and hepatology
Liang Z,He P,Han Y,Yun CC
PA5-114687 was used in Immunohistochemistry-immunofluorescence to identify LPA5 receptor as a potent regulator of the survival of stem cells and transit-amplifying cells in the intestine.
Mon Jun 20 00:00:00 EDT 2022
Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via Reducing the Reactive Oxygen Species and Apoptosis of Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Bao J,Qian Z,Liu L,Hong X,Che H,Wu X
PA5-114687 was used in Immunohistochemistry, Western Blot to investigate the impact of phosphorylation of eukaryotic initiation factor-2α (eIF2α)/activating transcription factor 4 (ATF4)/Indian hedgehog (Ihh) signalling in intervertebral disc degeneration.
Fri Jun 25 00:00:00 EDT 2021
Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via Reducing the Reactive Oxygen Species and Apoptosis of Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Bao J,Qian Z,Liu L,Hong X,Che H,Wu X
PA5-114687 was used in Immunohistochemistry, Western Blot to investigate the impact of phosphorylation of eukaryotic initiation factor-2α (eIF2α)/activating transcription factor 4 (ATF4)/Indian hedgehog (Ihh) signalling in intervertebral disc degeneration.
Fri Jun 25 00:00:00 EDT 2021
Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via Reducing the Reactive Oxygen Species and Apoptosis of Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Bao J,Qian Z,Liu L,Hong X,Che H,Wu X
PA5-114687 was used in Immunohistochemistry, Western Blot to investigate the impact of phosphorylation of eukaryotic initiation factor-2α (eIF2α)/activating transcription factor 4 (ATF4)/Indian hedgehog (Ihh) signalling in intervertebral disc degeneration.
Fri Jun 25 00:00:00 EDT 2021
Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via Reducing the Reactive Oxygen Species and Apoptosis of Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Bao J,Qian Z,Liu L,Hong X,Che H,Wu X
PA5-114687 was used in Immunohistochemistry, Western Blot to investigate the impact of phosphorylation of eukaryotic initiation factor-2α (eIF2α)/activating transcription factor 4 (ATF4)/Indian hedgehog (Ihh) signalling in intervertebral disc degeneration.
Fri Jun 25 00:00:00 EDT 2021
LncRNA HOXA11-AS aggravates the keloid formation by targeting miR-148b-3p/IGFBP5 axis.
Biochemical and biophysical research communications
Wang J,Shen J
PA5-114687 was used in Western Blot to show keloid progression can be promoted by long non-coding RNA homeobox HOXA11-AS.
Fri Dec 03 00:00:00 EST 2021
PAD4 inhibitor promotes DNA damage and radiosensitivity of nasopharyngeal carcinoma cells.
Environmental toxicology
Chen H,Wei L,Luo M,Wang X,Zhan Y,Mao Y,Huang C,Li J,Lu H
PA5-114687 was used in Immunohistochemistry to determine the effects of YW3-56 on the radiosensitivity of NPC cells.
Mon Nov 01 00:00:00 EDT 2021