Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Custom DNA Oligos
    • GeneArt Gene Synthesis Instant Designer
    • TaqMan Assay and Array Search
    • PCR Equipment and Supplies
    • Chromatography Columns and Cartridges
    • Lab Centrifuges
    • Molecular Biology Reagents and Kits
    • Lab Plasticware and Supplies
    • See all product categories
  • Applications
    • Chromatography
    • Cell Culture
    • Real-Time PCR
    • Mass Spectrometry
    • Lab Plasticware and Supplies
    • Electron Microscopy
    • Protein Biology
    • PCR
    • RNAi
    • Environmental
    • See all applications and techniques
  • Services
    • Custom Services
    • Enterprise-Level Lab Informatics
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • OEM and Commercial Supply
    • Training Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • See all services
  • Help and Support
    • Learning Centers
    • Contact Us
    • Change Location
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • Contact Us
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • AR Statement & Invoice Inquiry
            • Custom Products & Projects
            • Instrument Management

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Caveolin 1 Antibodies

          Invitrogen

          Caveolin 1 Polyclonal Antibody

          Advanced Verification
          4 Published Figures
          14 References
          View all (37) Caveolin 1 antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Protocols
          Questions & Answers
          Tech Support

          Cite Caveolin 1 Polyclonal Antibody

          • Antibody Testing Data (10)
          • Published Figures (4)
          • Advanced Verification (3)
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 17

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          Caveolin 1 Antibody (PA5-17447) in ICC/IF

          Immunofluorescence analysis of Caveolin 1 was performed using 70% confluent log phase HeLa cells treated with 2 nM of Paclitaxel for 24 hr. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Caveolin 1 Rabbit Polyclonal Antibody(Product # PA5-17447) at 1:100 di... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Caveolin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Caveolin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot, Immunoprecipitation (WB, IP)
          Caveolin 1 Antibody in Immunohistochemistry (IHC)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody
          Caveolin 1 Antibody
          Caveolin 1 Antibody
          Caveolin 1 Polyclonal Antibody

          Product Details

          PA5-17447

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          View 3 publications 3 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:250
          View 2 publications 2 publications

          Immunocytochemistry (ICC/IF)

          1:400
          View 4 publications 4 publications

          Flow Cytometry (Flow)

          1:50
          -

          Immunoprecipitation (IP)

          1:50
          View 1 publication 1 publication

          Affinity Purification (AP)

          -
          View 2 publications 2 publications

          Miscellaneous PubMed (Misc)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Bovine, Chicken, Hamster, Human, Mouse, Pig, Rat, Zebrafish

          Published species

          C. elegans, Chicken, Dog, Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to residues surrounding Glu20 of human caveolin-1
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          33 µg/mL

          Purification

          Antigen affinity chromatography, Protein A

          Storage buffer

          0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

          Contains

          no preservative

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10985023

          Product Specific Information

          It is not recommended to aliquot this antibody.

          This antibody is not cross-reactive with caveolin-2 or -3.

          Target Information

          Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CAV1; caveolae; caveolin 1, caveolae protein, 22kDa; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; Caveolin-1; cell growth-inhibiting protein 32; HGNC:1527; OTTHUMP00000196475; variant a; variant b

          View more View less

          Gene Aliases: BSCL3; CAV; Cav-1; CAV1; Caveolin-1; CGL3; LCCNS; MSTP085; PPH3; VIP21; wu:fc07c04

          View more View less

          UniProt ID: (Pig) Q6RVA9, (Chicken) P35431, (Bovine) P79132, (Human) Q03135, (Mouse) P49817

          View more View less

          Entrez Gene ID: (Pig) 404693, (Chicken) 373996, (Bovine) 281040, (Human) 857, (Mouse) 12389, (Rat) 25404, (Chinese hamster) 100753021, (Zebrafish) 323695

          View more View less

          Function(s)
          protein kinase binding ion channel binding binding, bridging receptor binding peptidase activator activity protein binding, bridging identical protein binding macromolecular complex binding protein heterodimerization activity Rac GTPase binding nitric-oxide synthase binding ATPase binding inward rectifier potassium channel inhibitor activity RNA polymerase I transcription factor binding patched binding structural molecule activity protein binding cholesterol binding enzyme binding syntaxin binding protein complex scaffold MDM2/MDM4 family protein binding SNARE binding kinase binding beta-catenin binding scaffold/adaptor protein
          Process(es)
          biological_process negative regulation of transforming growth factor beta receptor signaling pathway T cell costimulation receptor internalization negative regulation of endothelial cell proliferation cell differentiation regulation of cytosolic calcium ion concentration negative regulation of protein tyrosine kinase activity caveola assembly negative regulation of transcription from RNA polymerase II promoter inactivation of MAPK activity angiogenesis vasculogenesis response to hypoxia negative regulation of cytokine-mediated signaling pathway response to ischemia regulation of the force of heart contraction by chemical signal triglyceride metabolic process calcium ion transport regulation of smooth muscle contraction skeletal muscle tissue development lactation protein localization response to bacterium positive regulation of calcium ion transport into cytosol posttranscriptional regulation of gene expression positive regulation of gene expression positive regulation of cholesterol efflux positive regulation of peptidase activity receptor-mediated endocytosis of virus by host cell regulation of fatty acid metabolic process lipid storage regulation of blood coagulation positive regulation of cell migration negative regulation of epithelial cell differentiation negative regulation of protein ubiquitination positive regulation of protein ubiquitination negative regulation of protein binding positive regulation of protein binding response to progesterone negative regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation nitric oxide homeostasis positive regulation of toll-like receptor 3 signaling pathway insulin receptor internalization vasoconstriction negative regulation of tyrosine phosphorylation of STAT protein cholesterol homeostasis response to estrogen negative regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction negative regulation of pinocytosis negative regulation of nitric-oxide synthase activity positive regulation of NF-kappaB transcription factor activity response to calcium ion membrane depolarization mammary gland involution positive regulation of cell adhesion molecule production negative regulation of necroptotic process cellular response to exogenous dsRNA cellular response to hyperoxia cellular response to transforming growth factor beta stimulus basement membrane organization caveolin-mediated endocytosis regulation of heart rate by cardiac conduction angiotensin-activated signaling pathway involved in heart process negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway apoptotic signaling pathway regulation of membrane repolarization during action potential regulation of ventricular cardiac muscle cell action potential positive regulation of cold-induced thermogenesis regulation of ruffle assembly negative regulation of peptidyl-tyrosine autophosphorylation regulation of cell communication by electrical coupling involved in cardiac conduction positive regulation of ER-associated ubiquitin-dependent protein catabolic process positive regulation of gap junction assembly negative regulation of inward rectifier potassium channel activity receptor internalization involved in canonical Wnt signaling pathway regulation of entry of bacterium into host cell negative regulation of anoikis positive regulation of extrinsic apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway MAPK cascade positive regulation of endothelial cell proliferation cellular calcium ion homeostasis response to nutrient response to gamma radiation negative regulation of muscle cell apoptotic process vesicle organization cholesterol transport mammary gland development organ regeneration positive regulation of microtubule polymerization maintenance of protein location in cell cholesterol efflux wound healing response to drug negative regulation of tyrosine phosphorylation of Stat5 protein positive regulation of catalytic activity negative regulation of MAPK cascade protein localization to plasma membrane raft negative regulation of neuron differentiation positive regulation of endocytosis negative regulation of JAK-STAT cascade microtubule polymerization negative regulation of smooth muscle cell proliferation leukocyte migration regulation of nitric-oxide synthase activity protein homooligomerization response to glucocorticoid regulation of peptidase activity calcium ion homeostasis negative regulation of ERK1 and ERK2 cascade cellular response to mechanical stimulus cellular response to peptide hormone stimulus cellular senescence regulation of cardiac muscle cell action potential involved in regulation of contraction negative regulation of potassium ion transmembrane transport regulation of inward rectifier potassium channel activity protein localization to basolateral plasma membrane beta-catenin destruction complex disassembly negative regulation of cation channel activity regulation of the force of heart contraction endocytosis negative regulation of cell proliferation response to mechanical stimulus positive regulation of signal transduction negative regulation of signal transduction negative regulation of BMP signaling pathway negative regulation of MAP kinase activity protein oligomerization cellular response to starvation somitogenesis heart development dorsal/ventral pattern formation intestinal cholesterol absorption neuromast development regulation of defense response to virus notochord cell vacuolation cardiac muscle cell proliferation regulation of type I interferon-mediated signaling pathway cardiac muscle tissue regeneration
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us - 400 820 8982
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us About Us
          • Careers Careers
          • Investors Investors
          • News News
          • Social Responsibility Social Responsibility
          • Trademarks
          • Policies and Notices
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          China flag icon
          China
          本网站销售的所有产品均不得用于人类或动物之临床诊断或治疗,仅可用于工业或者科研等非医疗目的。
             电子营业执照 | 经营证照公示 | ICP备案号:沪ICP备11003924号 | 沪公网安备 31011502006935号

          Your items have has been added!


          Host server : magellan-search-blue-555ccb4fbd-26928:80/100.66.73.230:80.
          git-commit: 75f0c7d4cb44686da2af39b21f2e6446a20282e2
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-2025.12.99-1.0