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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KPDAEPRPGT QPPQARCRPN ADLELNDVIG L
Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 52%.
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Binder of Rho GTPases 3; Cdc42 effector protein 5
基因别名: BORG3; CDC42EP5; CEP5
Entrez Gene ID: (Human) 148170