Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Chloromycetin Recombinant Mouse Monoclonal Antibody (6E12)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
Chloromycetin Antibody (MA566581) in SDS-PAGE
SDS-PAGE characterization of Chloromycetin under reducing conditions. Lane M: Protein marker (kDa); Lane CAP: Purified Chloromycetin Recombinant Monoclonal (Product # MA566581). Chloromycetin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-395.
产品信息
MA566581
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6E12
抗原
Conjugate of CAP hapten and KLH.
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Chloromycetin, also known as chloramphenicol, is an antibiotic originally isolated from Streptomyces venezuelae. It functions by inhibiting protein synthesis in bacteria, specifically targeting the 50S ribosomal subunit, which prevents peptide bond formation. Structurally, chloramycetin is characterized by a nitrobenzene moiety and a dichloroacetyl group, contributing to its broad-spectrum antibacterial activity. It is synthesized chemically due to its complex structure, which includes both hydrophilic and hydrophobic components. Chloromycetin is primarily used to treat serious infections like typhoid fever and bacterial meningitis, although its use is limited due to potential side effects such as aplastic anemia. The antibiotic is unstable in high salt concentrations but remains intact in low counter ion solvents, with sedimentation coefficients of 18S and 25S observed in ribonucleoprotein particles. Its development marked a significant advancement in antibiotic therapy during the mid-20th century.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
