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Invitrogen
Chromogranin A Monoclonal Antibody (LK2H10)
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图: 1 / 28
Chromogranin A Antibody (MA5-13096) in ICC/IF
Immunofluorescent analysis of Chromogranin A (green) showing staining in the cytoplasm of SH-SY5Y cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a Chromogranin A monoclonal antibody (Product # MA5-13096) i... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-13096
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
LK2H10
抗原
Human pheochromocytoma
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-13096 targets Chromogranin A in IHC (P), ICC/IF and WB applications and shows reactivity with Human, Non-human primate, Porcine, Rabbit, and Rat samples.
The MA5-13096 immunogen is human pheochromocytoma.
靶标信息
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CgA; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; Chromogranin-A; CTNNB; DKFZp686D02253; FLJ25606; FLJ37923; MGC105435; pancreastatin; Pituitary secretory protein I; SP-I
基因别名: CHGA; ChrA
UniProt ID: (Pig) P04404, (Mouse) P26339
Entrez Gene ID: (Pig) 397540, (Rabbit) 100346049, (Rat) 24258, (Mouse) 12652
regulation of the force of heart contraction
organelle organization
positive regulation of cAMP metabolic process
ovulation cycle
negative regulation of vasodilation
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
negative regulation of neuron death
mast cell chemotaxis
mast cell cytokine production
negative regulation of catecholamine secretion
mast cell degranulation
mast cell activation
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
positive regulation of dense core granule biogenesis
positive regulation of cardiac muscle contraction
adrenergic receptor signaling pathway involved in cardiac muscle relaxation
positive regulation of relaxation of cardiac muscle
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