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Invitrogen
Cullin 1 Polyclonal Antibody
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Cullin 1 Antibody (71-8700) in WB
Western blot analysis was performed on whole cell extracts (30 µg lysate) of MDA-MB-231 (Lane 1), NTERA-2 (Lane 2), MCF-7 (Lane 3), A549 (Lane 4), and Caco-2 (Lane 5). The blots were probed with Anti- CUL1 Rabbit Polyclonal Antibody (Product # 71-8700, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A ~ 89 kDa band corresponding to CUL1 was observed across cell lines tested. Additionally ~68 kDa band was obse... View More
产品信息
71-8700
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
C. elegans,
Fruit fly,
Human,
Insect,
Mouse,
Non-human primate,
Virus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An 11 amino acid synthetic peptide derived from the extreme C-terminus of the human CUL1 protein. This peptide sequence is identical to Drosophila CUL1 (LIN-19) in 9/11 positions and in 7/11 residues with the CUL1 C. elegans and Dictyostelium discoidium homologs
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.1% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CUL1 gene ontology annotations related to this gene include animal organ morphogenesis; apoptotic process; cell proliferation; protein monoubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
protein monoubiquitination
cell cycle arrest
cell proliferation
negative regulation of cell proliferation
organ morphogenesis
viral process
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
T cell receptor signaling pathway
stress-activated MAPK cascade
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
intrinsic apoptotic signaling pathway
