Invitrogen

Cyclin A Recombinant Rabbit Monoclonal Antibody (SD2053)

Name: Cyclin A Recombinant Rabbit Monoclonal Antibody (SD2053)
Brand: Invitrogen
SKU: MA5-32399

查看其他8个Cyclin A抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

Cyclin A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

Cyclin A Antibody (MA5-32399) in IHC (P)

Immunohistochemical analysis of Cyclin A of paraffin-embedded Human colon cancer tissue using a Cyclin-A Monoclonal antibody (Product #MA5-32399). Counter stained with hematoxylin.

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Immunogen image

Immunogen Image Cyclin A Recombinant Rabbit Monoclonal Antibody (SD2053)

产品信息

MA5-32399

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

SD2053

抗原

Recombinant protein within Human Cyclin A1 + Cyclin A2 aa 253-440

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2809677

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.

仅用于科研。不用于诊断过程。未经明确授权不得转售。