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Invitrogen
DNASE2B Polyclonal Antibody
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DNASE2B Antibody (PA5-113211) in WB
Western Blot analysis of DNASE2B in multiple sample types using a DNASE2B polyclonal antibody (Product # PA5-113211) at a dilution of 1:2000. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:50,000. Sample types that were tested include: A549 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate .
产品信息
PA5-113211
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
偶联物
形式
Liquid
浓度
0.93 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deoxyribonuclease II beta; Deoxyribonuclease-2-beta; DNase II beta; DNase II-like acid DNase; DNase2-like acid DNase; Endonuclease DLAD; lysosomal DNase II
基因别名: DLAD; DNASE2B
UniProt ID: (Human) Q8WZ79
Entrez Gene ID: (Human) 58511
