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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: LQSDSELGRR LHKLGVSKVT QVDFLPREVV SYSKETQTPL ATHQSEEDEE DEE
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; DH IC-1; Dynein intermediate chain 1, cytosolic; dynein, cytoplasmic 1, intermediate chain 1; dynein, cytoplasmic, intermediate polypeptide 1
基因别名: DNCI1; DNCIC1; DYNC1I1
UniProt ID: (Human) O14576
Entrez Gene ID: (Human) 1780
分子生物学功能: microtubule or microtubule-binding cytoskeletal protein