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Invitrogen
DZIP3 Polyclonal Antibody
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DZIP3 Antibody (PA5-101568) in ICC/IF
Immunocytochemistry analysis of DZIP3 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with DZIP3 polyclonal antibody (Product # PA5-101568) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-101568
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DZIP3(Accession Q86Y13), corresponding to amino acid residues V682-E732.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total DZIP3.
靶标信息
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DAZ interacting protein 3, zinc finger; DAZ interacting zinc finger protein 3; DAZ-interacting protein 3; E3 ubiquitin-protein ligase DZIP3; hRUL138; human RNA-binding ubiquitin ligase of 138 kDa; protein phosphatase 1, regulatory subunit 66; RING-type E3 ubiquitin transferase DZIP3; RNA-binding RING-H2 protein-ubiquitin ligase; RNA-binding ubiquitin ligase of 138 kDa; UURF2 ubiquitin ligase; zinc finger DAZ interacting protein 3
基因别名: DZIP3; hRUL138; KIAA0675; PPP1R66; RGD1563278; UURF2
UniProt ID: (Human) Q86Y13
Entrez Gene ID: (Human) 9666, (Rat) 303963
