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Invitrogen
EDG4 Polyclonal Antibody
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EDG4 Antibody (PA5-90061) in WB
Western blot analysis of EDG4 in extracts of HL-60 cells. Samples were incubated with EDG4 Polyclonal antibody (Product # PA5-90061) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-90061
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human LPAR2 (NP_0047112)
偶联物
形式
Liquid
浓度
1.39 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FVVCWTPGQV VLLLDGLGCE SCNVLAVEKY FLLLAEANSL VNAAVYSCRD AEMRRTFRRL LCCACLRQST RESVHYTSSA QGGASTRIML PENGHPLMDS T; Positive Samples: HL-60; Cellular Location: Cell membrane, Cell surface, Multi-pass membrane protein
靶标信息
Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; G protein-coupled receptor; LPA receptor 2; LPA receptor EDG4; LPA2 Receptor; lysophosphatidic acid receptor Edg-4; lysophosphatidic acid receptor EDG4
基因别名: EDG-4; EDG4; LPA-2; LPA2
Entrez Gene ID: (Human) 9170
