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Invitrogen
ELF2 Polyclonal Antibody
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产品信息
PA5-52247
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MTSAVVDSGG TILELSSNGV ENQEESEKVS EYPAVIVEPV PSARLEQGYA AQVLVYDDET YMMQDVAEEQ EVETENVETV EASVHSSNAH CTDKTIEAAE ALLHMESPTC LRDSRSPEFI HAAMRPDVIT ETVVEVSTEE SEP
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 85%.
靶标信息
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: E74-like factor 2; E74-like factor 2 (ets domain transcription factor); ELF2; ets domain transcription factor; ets family transcription factor ELF2A2; ets family transcription factor ELF2C; ETS-related transcription factor Elf-2; New ETS-related factor
基因别名: 2610036A20Rik; A230104O07Rik; AW111824; BB183398; ELF2; EU32; NERF; NERF-1A; NERF-1a,b; NERF-1B; NERF-2
UniProt ID: (Human) Q15723, (Mouse) Q9JHC9
Entrez Gene ID: (Human) 1998, (Rat) 361944, (Mouse) 69257
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
positive regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
