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          • Primary Antibodies ›
          • ENPP1 Antibodies

          Invitrogen

          ENPP1 Polyclonal Antibody

          查看其他9个ENPP1抗体

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          Cite ENPP1 Polyclonal Antibody

          Additional Information:

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          • 抗体检测数据 (8)
          ENPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          ENPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 8

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          ENPP1 Antibody (PA5-119090) in IHC (P)

          Immunohistochemistry analysis of ENPP1 in paraffin-embedded Rat Intestine tissue. Samples were incubated with polyclonal antibody (Product # PA5-119090) at a dilution of 20 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
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          查看产品

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          ENPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ENPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ENPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ENPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ENPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ENPP1 Antibody in Western Blot (WB)
          ENPP1 Antibody in Western Blot (WB)
          ENPP1 Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          ENPP1 Polyclonal Antibody

          产品信息

          PA5-119090

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          0.01-2 µg/mL
          -

          免疫组化(石蜡) (IHC (P))

          5-20 µg/mL
          -
          产品规格

          种属反应

          Rat

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          Recombinant protein Ectonucleotide Pyrophosphatase/Phosphodiesterase 1. The antigen corresponds to amino acid range 568-793 of the target protein.
          3D表位/免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          0.5 mg/mL

          规格

          100 µg

          纯化类型

          Antigen affinity chromatography, Protein A

          保存液

          PBS, pH 7.4, with 50% glycerol

          内含物

          0.05% ProClin 300

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2903590

          靶标信息

          This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          Cite this product

          生物信息学

          蛋白别名: alkaline phosphodiesterase I; E-NPP 1; HGNC:3356; NPPase; nucleotide diphosphatase; nucleotide pyrophosphatase; OTTHUMP00000043194; phosphodiesterase I/nucleotide pyrophosphatase 1; plasma cell membrane glycoprotein PC-1; plasma-cell membrane glycoprotein PC-1

          查看更多 收起

          基因别名: Npps; Pc1

          查看更多 收起

          UniProt ID: (Rat) Q924C3

          查看更多 收起

          Entrez Gene ID: (Rat) 85496

          查看更多 收起

          功能
          nucleic acid binding 3',5'-cyclic-AMP phosphodiesterase activity exonuclease activity phosphodiesterase I activity nucleotide diphosphatase activity scavenger receptor activity insulin receptor binding calcium ion binding ATP binding phosphoric diester hydrolase activity zinc ion binding pyrophosphatase activity hydrolase activity phosphatase activity polysaccharide binding GTP diphosphatase activity UTP diphosphatase activity identical protein binding protein homodimerization activity metal ion binding nucleoside-triphosphate diphosphatase activity ATP diphosphatase activity cyclic-GMP-AMP hydrolase activity
          参与通路
          ossification vasculogenesis osteoblast differentiation kidney development liver development B-1 B cell homeostasis endochondral ossification morphogenesis of an epithelium response to dietary excess plasma cell differentiation inflammatory response to antigenic stimulus generation of precursor metabolites and energy glycolytic process fatty acid metabolic process phosphate-containing compound metabolic process immune response mitochondrion organization smoothened signaling pathway heart development sensory perception of sound adult walking behavior cell proliferation determination of adult lifespan adult locomotory behavior fibroblast growth factor receptor signaling pathway nucleoside triphosphate catabolic process response to wounding response to mechanical stimulus gene expression magnesium ion homeostasis microglia differentiation Wnt signaling pathway vesicle-mediated transport organic phosphonate metabolic process spinal cord development cerebellum development striatum development hippocampus development olfactory bulb development cerebral cortex development central nervous system myelination T cell differentiation macrophage differentiation negative regulation of ossification bone mineralization negative regulation of cell growth osteoclast differentiation melanocyte differentiation regulation of bone mineralization negative regulation of bone mineralization inorganic diphosphate transport cellular phosphate ion homeostasis axon regeneration biomineral tissue development response to magnesium ion response to insulin cellular response to insulin stimulus response to ATP tooth mineralization response to vitamin B6 post-embryonic forelimb morphogenesis multicellular organism growth bone mineralization involved in bone maturation aorta development ligamentous ossification response to platelet-derived growth factor collagen-activated signaling pathway hormone metabolic process middle ear morphogenesis odontogenesis glucose homeostasis mRNA transcription from RNA polymerase II promoter defense response to protozoan skin development fat cell differentiation bone resorption negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process ATP metabolic process negative regulation of glucose import negative regulation of insulin receptor signaling pathway bone remodeling animal organ development 3'-phosphoadenosine 5'-phosphosulfate metabolic process sensory perception of temperature stimulus sensory perception of mechanical stimulus cartilage development neuron apoptotic process phosphate ion homeostasis calcium ion homeostasis long-term synaptic potentiation bone trabecula formation bone development endochondral bone morphogenesis adipose tissue development fat pad development artery development articular cartilage development protein poly-ADP-ribosylation mucus secretion vitamin D3 metabolic process cellular response to mechanical stimulus cellular response to cAMP diphosphate metabolic process cellular response to acidic pH cementum mineralization cellular response to transforming growth factor beta stimulus hematopoietic stem cell migration to bone marrow oligodendrocyte apoptotic process glucose import across plasma membrane bone growth response to Gram-positive bacterium inhibition of non-skeletal tissue mineralization microglial cell migration response to sodium phosphate cellular response to sodium phosphate vascular associated smooth muscle cell migration vascular associated smooth muscle cell proliferation
          It has to be done as per old AB suggested Products section.

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