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Invitrogen
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Immunogen sequence: PLHININKAE EKKVSEKTLQ TPLLPSPVAD HVKCNILKAQ LENASRVNIQ GGKEESPFVN INKKSSLQDA SVRSPIPIRV ETAQPAVEKP EIKPPRVRKL TRQYSFDEDD LPP
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Band 4.1-like protein 4B; Erythrocyte membrane protein band 4.1-like 4B; FERM-containing protein CG1; Protein EHM2
基因别名: CG1; EHM2; EPB41L4B; LULU2
UniProt ID: (Human) Q9H329
Entrez Gene ID: (Human) 54566