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Abnova
EPHA7 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
H00002045-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EPHA7 (AAH27940.1, 1 a.a. approximately 279 a.a) full-length human protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVFQTRYPSW IILCYIWLLR FAHTGEAQAA KEVLLLDSKA QQTELEWISS PPNGWEEISG LDENYTPIRT YQVCQVMEPN QNNWLRTNWI SKGNAQRIFV ELKFTLRDCN SLPGVLGTCK ETFNLYYYET DYDTGRNVRE NLYVKIDTIA ADESFTQGDL GERKMKLNTE VREIGPLSKK GFYLAFQDVG ACIALVSVKV YYKKCWSIIE NLAIFPDTVT GSEFSSLVEV RGTCVSSAEE EAENAPRMHC SAEGEWLVPI GKCICKAGYQ QKGDTCECK
Target Information
EPHA7 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA7 is involved in embryonic development. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epa7; EPH homology kinase 3; Eph homology kinase-3; EPH-like kinase 11; EPHA7-S; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; unnamed protein product
Gene Aliases: EHK-3; EHK3; EK11; HEK11
UniProt ID: (Human) Q15375
Entrez Gene ID: (Human) 2045
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
ephrin receptor activity
GPI-linked ephrin receptor activity
transmembrane-ephrin receptor activity
protein binding
ATP binding
axon guidance receptor activity
growth factor binding
chemorepellent activity
ephrin receptor binding
transmembrane receptor protein tyrosine kinase signaling pathway
axon guidance
brain development
phosphorylation
regulation of cell-cell adhesion
regulation of protein autophosphorylation
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
ephrin receptor signaling pathway
negative regulation of collateral sprouting
branching morphogenesis of a nerve
regulation of peptidyl-tyrosine phosphorylation
modulation of synaptic transmission
negative chemotaxis
negative regulation of protein kinase B signaling
negative regulation of synapse assembly
regulation of ERK1 and ERK2 cascade
regulation of postsynapse organization
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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