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Immunogen sequence: RVGLIHDVFQ LVGAGRLTLD KALDMTYYLQ HETSSPALLE GLSYLESFYH MMDRRNISDI SENLKRYLLQ YFKPVID
Highest antigen sequence identity to the following orthologs: Mouse - 36%, Rat - 36%.
Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex class I molecules rely on aminopeptidases such as ERAP1 and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum following cleavage in the cytoplasm by tripeptidyl peptidase II.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endoplasmic reticulum aminopeptidase 2; FLJ23633; FLJ23701; FLJ23807; L-RAP; Leukocyte-derived arginine aminopeptidase
基因别名: ERAP2; L-RAP; LRAP
UniProt ID: (Human) Q6P179
Entrez Gene ID: (Human) 64167
分子生物学功能: metalloprotease