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          • Primary Antibodies ›
          • Endothelin A Receptor Antibodies

          7TM Antibodies

          ETA, Endothelin Receptor A Polyclonal Antibody

          3 References
          View all (7) Endothelin A Receptor antibodies

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          Cite ETA, Endothelin Receptor A Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (5)
          ETA, Endothelin Receptor A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          ETA, Endothelin Receptor A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          ETA, Endothelin Receptor A Antibody (7TM0219N-IC) in IHC (P)

          Immunohistochemical identification of Endothelin Receptor A in mouse heart. Sections were dewaxed, microwaved in citric acid, and incubated with anti-ETA (Endothelin receptor A) antibody (7TM0219N-IC) at a dilution of 1:100. Sections were then sequentially treated with biotinylated anti-rabbit IgG and avidin-biotin solution. Color was developed by incubation in 3-amino-9-ethylcarbazole (AEC) , and sections ... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          ETA, Endothelin Receptor A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ETA, Endothelin Receptor A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ETA, Endothelin Receptor A Antibody in Immunocytochemistry (ICC/IF)
          ETA, Endothelin Receptor A Antibody in Western Blot (WB)
          ETA, Endothelin Receptor A Antibody in Western Blot (WB)
          ETA, Endothelin Receptor A Polyclonal Antibody

          Product Details

          7TM0219N-IC

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100
          -

          Immunocytochemistry (ICC/IF)

          1:200
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide with sequence KNHDQNNHNTDRSSHKDSMN corresponds to amino acids 408 - 427 in human, mouse and rat ETA.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          Dulbecco's PBS, pH 7.4

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Endothelin A; endothelin A receptor; endothelin receptor subtype A; Endothelin receptor type A; Endothelin-1 receptor; endothelin-1-specific receptor; ET-A; ET-AR; ET-AR delta 3-4; ET-AR delta 4; G protein-coupled receptor; G-protein coupled receptor; G-protein coupled receptor 10; unnamed protein product

          View more View less

          Gene Aliases: EDNRA; Endor; ET-A; ET-AR; ETA; ETA-R; ETAR; ETRA; Gpcr10; hET-AR; MFDA; RGD1559432

          View more View less

          UniProt ID: (Human) P25101, (Rat) P26684, (Mouse) Q61614

          View more View less

          Entrez Gene ID: (Human) 1909, (Rat) 24326, (Mouse) 13617

          View more View less

          Function(s)
          phosphatidylinositol phospholipase C activity G-protein coupled receptor activity endothelin receptor activity protein binding protein tyrosine kinase activity signal transducer activity
          Process(es)
          patterning of blood vessels response to hypoxia in utero embryonic development histamine secretion positive regulation of protein phosphorylation glomerular filtration positive regulation of cytosolic calcium ion concentration protein kinase C-activating G-protein coupled receptor signaling pathway Rho protein signal transduction heart development aging respiratory gaseous exchange regulation of blood pressure positive regulation of cell proliferation neural crest cell development response to organic cyclic compound artery smooth muscle contraction glucose transport sensory perception of pain negative regulation of cAMP biosynthetic process response to lipopolysaccharide vasoconstriction positive regulation of odontogenesis negative regulation of apoptotic process penile erection response to morphine fibroblast proliferation enteric nervous system development smooth muscle cell proliferation regulation of epithelial cell proliferation positive regulation of inflammatory response positive regulation of release of sequestered calcium ion into cytosol positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway positive regulation of calcium ion transport maternal process involved in parturition head development positive regulation of ERK1 and ERK2 cascade cellular response to mechanical stimulus endothelin receptor signaling pathway positive regulation of neutrophil chemotaxis positive regulation of kidney development signal transduction G-protein coupled receptor signaling pathway mitotic cell cycle angiogenesis blood vessel remodeling response to amphetamine regulation of heart rate heart process cardiac chamber formation left ventricular cardiac muscle tissue morphogenesis atrial cardiac muscle tissue development cardiac neural crest cell migration involved in outflow tract morphogenesis noradrenergic neuron differentiation cellular calcium ion homeostasis smooth muscle contraction mitochondrion organization activation of adenylate cyclase activity adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway axon guidance cell proliferation response to wounding gene expression regulation of glucose transport neural crest cell differentiation neural crest cell fate commitment vascular smooth muscle contraction neuron remodeling heparin metabolic process thyroid gland development neuron projection development glomerulus development cellular response to oxidative stress embryonic heart tube development aorta development norepinephrine metabolic process middle ear morphogenesis positive regulation of I-kappaB kinase/NF-kappaB signaling cellular response to human chorionic gonadotropin stimulus developmental pigmentation sympathetic nervous system development axon extension embryonic skeletal system development neuromuscular process sodium ion homeostasis canonical Wnt signaling pathway face development axonogenesis involved in innervation establishment of endothelial barrier pharyngeal arch artery morphogenesis renal sodium ion absorption calcium ion transmembrane transport cellular response to follicle-stimulating hormone stimulus cellular response to luteinizing hormone stimulus protein transmembrane transport glomerular endothelium development glomerular visceral epithelial cell differentiation endothelin receptor signaling pathway involved in heart process renal albumin absorption vascular smooth muscle cell development mesenchymal cell apoptotic process cellular response to toxic substance sympathetic neuron axon guidance cAMP/PKA signal transduction semaphorin-plexin signaling pathway involved in axon guidance glomerular visceral epithelial cell apoptotic process meiotic cell cycle process involved in oocyte maturation cranial skeletal system development response to acetylcholine regulation of protein localization to cell leading edge
          It has to be done as per old AB suggested Products section.

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