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Invitrogen
FAM122B Polyclonal Antibody
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产品信息
PA5-34720
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human FAM122B. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A549, HeLa, HepG2, HCT116, mouse liver.
Predicted reactivity: Mouse (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
FAM122B (Family with Sequence Similarity 122 Member B) is a gene located on chromosome 9 that encodes a protein involved in cellular signaling and regulation. FAM122B is known to interact with protein phosphatase 2A (PP2A), a critical enzyme in multiple signaling pathways, thereby impacting various cellular functions such as growth, division, and apoptosis. This interaction is pivotal for the modulation of PP2A activity, which in turn influences numerous downstream signaling processes. Studies have indicated that FAM122B may play a role in cancer biology, particularly in the regulation of oncogenic pathways. Dysregulation of FAM122B expression has been observed in certain cancers, suggesting its potential involvement in tumor progression and as a biomarker for diagnosis or prognosis. Furthermore, the gene's expression patterns indicate its importance in normal cellular homeostasis and the maintenance of cellular signaling balance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: erg-3; ets-related; p55; PABIR family member 2; protein FAM122B; RP11-308B5.5; synoviocyte proliferation associated in collagen-induced arthritis 2; TMPRSS2/ERG fusion
基因别名: 4632404H22Rik; AI256344; FAM122B; PABIR2; SPACIA2
UniProt ID: (Human) Q6PIM2, (Mouse) Q6NZE7
Entrez Gene ID: (Human) 159090, (Mouse) 78755
