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Invitrogen
FAM132A Polyclonal Antibody
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产品信息
PA5-54980
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DAHMTWLNFV RRPDDGALRK RCGSRDKKPR DLFGPPGPPG AEVTAETLLH EFQELLKEAT ERRFSGLLD
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 65%.
靶标信息
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adipolin; Adipose-derived insulin-sensitizing factor; C1q and TNF related protein 12; C1q domain containing 2; C1q/TNF-related protein 12; Complement C1q tumor necrosis factor-related protein 12; family with sequence similarity 132, member A; protein FAM132A
基因别名: C1QDC2; C1QTNF12; CTRP12; FAM132A
UniProt ID: (Human) Q5T7M4
Entrez Gene ID: (Human) 388581
positive regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of gluconeogenesis
regulation of glucose import
positive regulation of glucose import
positive regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
positive regulation of protein kinase B signaling
