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Invitrogen
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Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytosolic iron-sulfur assembly component 2A; family with sequence similarity 96, member A; MIP18 family protein FAM96A
基因别名: 5730536A07Rik; CIA2A; CIAO2A; FAM96A
UniProt ID: (Human) Q9H5X1, (Mouse) Q9DCL2
Entrez Gene ID: (Human) 84191, (Mouse) 68250