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Invitrogen
FEM1A Polyclonal Antibody
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产品信息
PA1-24858
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-HIPEKLETFVSLHR, from the C Terminus.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX10911-PEP)..
PA1-24858 is expected to cross react with mouse Fem1C (100% conserved) due to sequence homology.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp762M136; FEM1-alpha; FEM1-alpha-A; FEM1a; FEM1a-A; feminization 1 homolog a; Prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; Protein fem-1 homolog A-A
基因别名: AW611390; Eprap; Fem1a; Fem1aa
UniProt ID: (Rat) Q4V890, (Mouse) Q9Z2G1
Entrez Gene ID: (Rat) 316131, (Mouse) 14154
