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Invitrogen
FES Polyclonal Antibody
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FES Antibody (PA5-95067) in WB
Western blot analysis of FES in Lane 1: HeLa whole cell lysate (40 µg), Lane 2: 293T whole cell lysate (40 µg), Lane 3: SKOV whole cell lysate (40 µg), Lane 4: A549 whole cell lysate (40 µg). Samples were incubated with FES polyclonal antibody (Product # PA5-95067).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-95067
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human FES (644-663aa FLTFLRTEGARLRVKTLLQM).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA whole cell, 293T whole cell, SKOV whole cell, A549 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
FES (FPS) is a tyrosine protein kinase that is required for maintenance of cellular transformation. Its chromosomal location is linked to a specific translocation event identified in patients with acute promyelocytic leukemia, and it is also involved in normal hematopoiesis. Alternative splicing results in multiple variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 2.7.10.2; feline sarcoma oncogene; Proto-oncogene c-Fes; proto-oncogene tyrosine-protein kinase Fes/Fps; tyrosine kinase Fps/Fes; Tyrosine-protein kinase Fes/Fps; Variant 4
基因别名: AI586313; BB137047; c-fes; Fes; FPS; RGD1564385
UniProt ID: (Mouse) P16879
Entrez Gene ID: (Mouse) 14159, (Rat) 361597
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
microtubule binding
lipid binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
immunoglobulin receptor binding
phosphatidylinositol binding
microtubule bundle formation
protein phosphorylation
chemotaxis
cell adhesion
transmembrane receptor protein tyrosine kinase signaling pathway
regulation of cell shape
positive regulation of neuron projection development
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
regulation of cell adhesion
positive regulation of microtubule polymerization
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
regulation of mast cell degranulation
innate immune response
regulation of cell differentiation
positive regulation of myeloid cell differentiation
protein autophosphorylation
centrosome organization
regulation of cell motility
positive regulation of actin cytoskeleton reorganization
epidermal growth factor receptor signaling pathway
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