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Invitrogen
FEZF1 Polyclonal Antibody
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FEZF1 Antibody (PA5-97744) in IHC (P)
Immunohistochemical analysis of FEZF1 in paraffin embedded human brain tissue using a FEZF1 polyclonal antibody (Product # PA5-97744) at a dilution of 1:400. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detect... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-97744
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Fez family zinc finger protein 1 protein (1-115AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
3.915 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fez family zinc finger protein 1; unnamed protein product; Zinc finger protein 312B
基因别名: FEZ; FEZF1; HH22; ZNF312B
UniProt ID: (Human) A0PJY2
Entrez Gene ID: (Human) 389549
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
nervous system development
axon guidance
negative regulation of cell proliferation
telencephalon development
olfactory bulb development
forebrain anterior/posterior pattern specification
central nervous system neuron differentiation
cell differentiation
neuron differentiation
forebrain development
cell dedifferentiation
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of neurogenesis
interneuron migration
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
