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Abnova
FGL2 Polyclonal Antibody, MaxPab™
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FGL2 Antibody (H00010875-D01P) in WB
Western Blot analysis of FGL2 expression in transfected 293T cell line (H00010875-T02) by FGL2 MaxPab polyclonal antibody.
Lane 1: FGL2 transfected lysate(50.20 KDa).
Lane 2: Non-transfected lysate.
Lane 1: FGL2 transfected lysate(50.20 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00010875-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FGL2 (NP_006673.1, 1 a.a. approximately 439 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MKLANWYWLS SAVLATYGFL VVANNETEEI KDERAKDVCP VRLESRGKCE EAGECPYQVS LPPLTIQLPK QFSRIEEVFK EVQNLKEIVN SLKKSCQDCK LQADDNGDPG RNGLLLPSTG APGEVGDNRV RELESEVNKL SSELKNAKEE INVLHGRLEK LNLVNMNNIE NYVDSKVANL TFVVNSLDGK CSKCPSQEQI QSRPVQHLIY KDCSDYYAIG KRSSETYRVT PDPKNSSFEV YCDMETMGGG WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL RIDLEDFNGV ELYALYDQFY VANEFLKYRL HVGNYNGTAG DALRFNKHYN HDLKFFTTPD KDNDRYPSGN CGLYYSSGWW FDACLSANLN GKYYHQKYRG VRNGIFWGTW PGVSEAHPGG YKSSFKEAKM MIRPKHFKP
靶标信息
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fibrinogen-like 2; Fibrinogen-like protein 2; Fibroleukin; pT49
基因别名: FGL2; pT49; T49
UniProt ID: (Human) Q14314
Entrez Gene ID: (Human) 10875
