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Invitrogen
FIP200 Polyclonal Antibody
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FIP200 Antibody (PA5-35961) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of FIP200 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 10 min. Green: FIP200 Polyclonal Antibody (Product # PA5-35961) diluted at 1:200. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
PA5-35961
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the N-terminus region of human FIP200. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Recommended positive controls: 293T, A431, human FIP200-transfected 293T.
Predicted reactivity: Mouse (86%), Rat (87%), Rhesus Monkey (98%), Bovine (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 200 kDa FAK family kinase-interacting protein; FAK family kinase-interacting protein of 200 kDa; FIP200; phosphatase 1, regulatory subunit 131; RB1-inducible coiled-coil 1; RB1-inducible coiled-coil protein 1
基因别名: ATG17; CC1; FIP200; KIAA0203; PPP1R131; RB1CC1; RBICC
UniProt ID: (Human) Q8TDY2
Entrez Gene ID: (Human) 9821
autophagosome assembly
liver development
positive regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
autophagy
cell cycle
JNK cascade
heart development
regulation of autophagy
macroautophagy
positive regulation of cell size
negative regulation of extrinsic apoptotic signaling pathway
