Search Thermo Fisher Scientific
MA1-5771 detects FMR1 in drosophila samples (does not cross react with human). Western blot detects a band of approximately 85kDa (predicted molecular weight: 82kDa).
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cg 6203 gene product from transcript cg6203-rc; CG6203-PA; CG6203-PB; CG6203-PC; CG6203-PD; CG6203-PE; CG6203-PF; CG6203-PG; CG6203-PH; CG6203-PI; CG6203-PJ; CG6203-PK; dFMR; dFMR1; drosophila fragile X mental retardation protein; Fmr1-PA; Fmr1-PB; Fmr1-PC; Fmr1-PD; Fmr1-PE; Fmr1-PF; Fmr1-PG; Fmr1-PH; Fmr1-PI; Fmr1-PJ; Fmr1-PK; fragile X; fragile X mental retardation; fragile X mental retardation 1; fragile X mental retardation gene; fragile X mental retardation protein; fragile X mental retardation protein 1; fragile X mental retardation related 1; Fragile X messenger ribonucleoprotein 1 homolog; fragile X protein; fragile x related; fragile X related protein; fragile X retardation 1 protein; fragile X-related; fragile-X; Fragile-X mental retardation 1; Fragile-X mental retardation protein; Fragile-X-related; FXR; MGC87458
基因别名: AT24755; BcDNA:GM08679; CG6203; dFMR; DFmr1; DFMRP; dFXR; dFXR1; dFXRP; Dmel\CG6203; Dmel_CG6203; dmfr1; EP(3)3517; FMR; FMR1; FMRP; FXR
UniProt ID: (Fruit fly) Q9NFU0
Entrez Gene ID: (Fruit fly) 37528
分子生物学功能: translation factor