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Recommended positive controls: 293T, A431.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Folate receptor 4; folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); Folate receptor delta; FR-delta; IZUMO1 receptor protein JUNO; probable folate receptor delta; Sperm-egg fusion protein Juno
基因别名: Folbp3; FOLR4; IZUMO1R; JUNO
UniProt ID: (Human) A6ND01
Entrez Gene ID: (Human) 390243