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Invitrogen
FOLR4 Polyclonal Antibody
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FOLR4 Antibody (PA5-80747) in WB
Western Blot using FOLR4 Polyclonal Antibody (Product # PA5-80747) at 1:500 dilution. Lane A: MCF7 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti- RabbitIgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 29 kDa. Observed band size: 35 kDa. (We are unsure of the identity of these extra bands).
产品信息
PA5-80747
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the center region of the Human FOLR4/Folate Receptor 4
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human FOLR4/Folate Receptor 4.
靶标信息
FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Folate receptor 4; folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); Folate receptor delta; FR-delta; IZUMO1 receptor protein JUNO; probable folate receptor delta; Sperm-egg fusion protein Juno
基因别名: Folbp3; FOLR4; IZUMO1R; JUNO
UniProt ID: (Human) A6ND01
Entrez Gene ID: (Human) 390243
