Invitrogen

FZD8 Polyclonal Antibody

Name: FZD8 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-47071

查看其他11个FZD8抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image FZD8 Polyclonal Antibody

产品信息

PA5-47071

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1 µg/mL

免疫组化 (IHC)

5-15 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-8 Ala25-Pro173

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2607397

产品详细信息

In direct ELISAs, approximately 5% cross-reactivity with recombinant mouse (rm) Frizzled-9 is observed and less than 1% cross-reactivity with rmFrizzled-1, rmFrizzled-2, rmFrizzled-3, rmFrizzled-4, rmFrizzled-6, and rmFrizzled-7 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。