Search
Invitrogen
GABRB1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
FIGURE: 1 / 1
GABRB1 Antibody (PA5-90886) in WB
Western blot analysis of GABRB1 in extracts of various cell lines. Samples were incubated with GABRB1 Polyclonal antibody (Product # PA5-90886) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-90886
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human GABA A Receptor beta 1 (GABRB1) (NP_0008032)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.11 mg/mL
Amount
111 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: U-251MG, mouse brain, rat brain
Immunogen sequence: IPYVKAIDIY LMGCFVFVFL ALLEYAFVNY IFFGKGPQKK GASKQDQSAN EKNKLEMNKV QVDAHGNILL STLEIRNETS GSEVLTSVSD PKATMYSYDS A
Target Information
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GABA(A) receptor; GABA(A) receptor subunit beta-1; GABA(A)R beta-1; GABA-RB; GABAAR subunit beta-1; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 1; gamma-aminobutyric acid (GABA) A receptor, subunit beta 1; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1; Gamma-aminobutyric acid receptor beta 1; gamma-aminobutyric acid type A receptor beta 1 subunit; gamma-aminobutyric acid type A receptor beta1 subunit; GBRB1; unnamed protein product
Gene Aliases: B230208N19Rik; DEE45; EIEE45; Gabrb-1; GARB1
UniProt ID: (Human) P18505, (Rat) P15431, (Mouse) P50571
Entrez Gene ID: (Human) 2560, (Rat) 25450, (Mouse) 14400
transmembrane signaling receptor activity
GABA-A receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
anion channel activity
ligand-gated ion channel activity
GABA-gated chloride ion channel activity
neurotransmitter receptor activity
GABA receptor binding
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
G protein-coupled neurotransmitter receptor activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
ion transport
chloride transport
signal transduction
G-protein coupled receptor signaling pathway
gamma-aminobutyric acid signaling pathway
response to toxic substance
central nervous system neuron development
response to progesterone
ion transmembrane transport
regulation of membrane potential
ovulation cycle
synaptic transmission, GABAergic
regulation of postsynaptic membrane potential
cellular response to histamine
regulation of presynaptic membrane potential
chloride transmembrane transport
negative regulation of synaptic transmission, GABAergic
extrasynaptic signaling via GABA
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support