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Invitrogen
GABRB1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-95657
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein from the cytoplasmic loop of the beta 1 subunit
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.15 mg/mL
Amount
15 µg
Purification
Antigen Affinity Chromatography
Storage buffer
10mM HEPES, pH 7.5, with 100µg/mL BSA, 50% glycerol, 0.15M NaCl
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antigen Affinity Purified from Pooled Serum
Target Information
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA(A) receptor; GABA(A) receptor subunit beta-1; GABA(A)R beta-1; GABA-RB; GABAAR subunit beta-1; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 1; gamma-aminobutyric acid (GABA) A receptor, subunit beta 1; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1; Gamma-aminobutyric acid receptor beta 1; gamma-aminobutyric acid type A receptor beta 1 subunit; GBRB1
Gene Aliases: B230208N19Rik; Gabrb-1; GARB1
UniProt ID: (Rat) P15431, (Mouse) P50571
Entrez Gene ID: (Rat) 25450, (Mouse) 14400
transmembrane signaling receptor activity
GABA-A receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
anion channel activity
ligand-gated ion channel activity
GABA-gated chloride ion channel activity
neurotransmitter receptor activity
GABA receptor binding
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
G protein-coupled neurotransmitter receptor activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
ion transport
chloride transport
signal transduction
G-protein coupled receptor signaling pathway
gamma-aminobutyric acid signaling pathway
response to toxic substance
central nervous system neuron development
response to progesterone
ion transmembrane transport
regulation of membrane potential
ovulation cycle
synaptic transmission, GABAergic
regulation of postsynaptic membrane potential
cellular response to histamine
regulation of presynaptic membrane potential
chloride transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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