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Bethyl Laboratories
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This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-glucosidase 2; carbohydrate processing enzyme of the endoplasmic reticulum; glucosidase II alpha-subunit; Glucosidase II subunit alpha; Neutral alpha-glucosidase AB
基因别名: AU042638; G2AN; GANAB; GIIA; GLUII; KIAA0088; mKIAA0088
UniProt ID: (Human) Q14697, (Mouse) Q8BHN3
Entrez Gene ID: (Human) 23193, (Mouse) 14376