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Immunogen sequence: KHYSLVQWQEF AGQNPDCLEH LAASSGTGSS DFEQLEQILE AIPQVKYIC
Highest antigen sequence identity to the following orthologs - mouse 88%, rat 90%.
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (PubMed:12009299, PubMed:12669231, PubMed:16359702, PubMed:22037469). Plays a role in modulating cellular differentiation (PubMed:12669231).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GMP reductase 2; GMPR 2; Guanosine 5'-monophosphate oxidoreductase 2; Guanosine monophosphate reductase 2; guanosine monophosphate reductase isolog
基因别名: GMPR 2; GMPR2
UniProt ID: (Human) Q9P2T1
Entrez Gene ID: (Human) 51292
分子生物学功能: reductase