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Invitrogen
GPI Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-82874
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LGIWYINCFG CETHAMLPYD QYLHRFAAYF QQGDMESNGK YITKSGTRVD HQTGPIVWGE PGTNGQHAFY QLIHQGTKMI PCDFLIPVQT
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 94%.
靶标信息
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: autocrine motility factor; D-hexose-6-phosphate anomerase; glucose-6-phosphate C2-epimerase; hexose monophosphate isomerase; hexosephosphate isomerase; neuroleukin; oxoisomerase; phosphoglucose isomerase; phosphohexomutase; phosphohexose isomerase; phosphosaccharomutase; sperm antigen; sperm antigen-36; unnamed protein product
基因别名: AMF; CNSHA4; GNPI; NLK; PGI; PHI; SA-36; SA36
UniProt ID: (Human) P06744
Entrez Gene ID: (Human) 2821
positive regulation of immunoglobulin production
carbohydrate metabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
glycolytic process
humoral immune response
hemostasis
learning or memory
positive regulation of endothelial cell migration
response to estradiol
response to progesterone
response to testosterone
response to immobilization stress
response to muscle stretch
negative regulation of apoptotic process
response to cadmium ion
glucose 6-phosphate metabolic process
canonical glycolysis
carbohydrate derivative metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
