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PA1-32647 detects GPCR GPR12 from human samples.
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ18149; FLJ97704; G-protein coupled receptor 12; MGC138349; MGC138351; protein phosphatase 1, regulatory subunit 84
基因别名: GPCR12; GPCR21; GPR12; PPP1R84
UniProt ID: (Human) P47775
Entrez Gene ID: (Human) 2835