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Invitrogen
GPR12 Polyclonal Antibody
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产品信息
PA5-32793
产品规格
种属反应
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 1st extracellular domain of human GPR12 / GPCR12.
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Pig, Opossum (100%); Bat, Elephant, Rabbit (94%); Turkey, Chicken (88%); Platypus, Xenopus (81%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ18149; FLJ97704; G protein-coupled receptor 12; G-protein coupled receptor 12; GPCR01; MGC138349; MGC138351; protein phosphatase 1, regulatory subunit 84; R334
基因别名: Gpcr01; GPCR12; Gpcr20; GPCR21; GPR12; PPP1R84
UniProt ID: (Human) P47775, (Mouse) P35412, (Rat) P30951
