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IHC(P) analysis shows positive staining of GPR6 in human ileum mucosa and enteric ganglion tissue.
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR6 is an orphan, constitutively active G-coupled protein receptor, involved in a wide array of functions such as neurite growth, amyloid processing and appetitive learning. GPR6 is predominantly expressed in neurons in the striatum of the brain. GPR6 was found to be expressed on the cell surface and in intracellular compartments.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G-protein coupled receptor 6; RCNL3; Sphingosine 1-phosphate receptor GPR6
基因别名: GPR6
UniProt ID: (Human) P46095
Entrez Gene ID: (Human) 2830