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Invitrogen
GPR6 Polyclonal Antibody
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GPR6 Antibody (PA5-90013) in WB
Western blot analysis of GPR6 in extracts of U-251MG cells. Samples were incubated with GPR6 Polyclonal antibody (Product # PA5-90013) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-90013
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 253-362 of human GPR6 (NP_0052751)
偶联物
形式
Liquid
浓度
1.3 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: WRHAHQIALQ QHCLAPPHLA ATRKGVGTLA VVLGTFGASW LPFAIYCVVG SHEDPAVYTY ATLLPATYNS MINPIIYAFR NQEIQRALWL LLCGCFQSKV PFRSRSPSEV; Positive Samples: U-251MG; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR6 is an orphan, constitutively active G-coupled protein receptor, involved in a wide array of functions such as neurite growth, amyloid processing and appetitive learning. GPR6 is predominantly expressed in neurons in the striatum of the brain. GPR6 was found to be expressed on the cell surface and in intracellular compartments.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G-protein coupled receptor 6; RCNL3; Sphingosine 1-phosphate receptor GPR6
基因别名: AI852874; Gm233; GPR6
UniProt ID: (Human) P46095, (Mouse) Q6YNI2
Entrez Gene ID: (Human) 2830, (Mouse) 140741
