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Invitrogen
HPS5 Polyclonal Antibody
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HPS5 Antibody (PA5-88334) in WB
Western blot analysis of HPS5 in extracts of various cell lines. Samples were incubated with HPS5 Polyclonal antibody (Product # PA5-88334) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88334
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 340-600 of human HPS5 (NP_0091473)
偶联物
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: IISSRRGSQS DEDSCSLHSQ TLSEDERFKE FTSQQEEDLP DQCCGSHGNE DNVSHAPVMF ETDKNETFLP FGIPLPFRSP SPLVSLQAVK ESVSSFVRKT TEKIGTLHTS PDLKVRPELR GDEQSCEEDV SSDTCPKEED TEEEKEVTSP PPEEDRFQEL KVATAEAMTK LQDPLVLFES ESLRMVLQEW LSHLEKTFAM KDFSGVSDTD NSSMKLNQDV LLVNESKKGI LDEDNEKEKR DSLGNEESVD KTACECVRSP R; Positive Samples: Jurkat, 293T, B cells; Cellular Location: Cytoplasm, cytosol
靶标信息
May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha integrin binding protein 63; Alpha-integrin-binding protein 63; BLOC-2 complex member HPS5; Hermansky-Pudlak syndrome 5 protein; Ru2; Ruby-eye protein 2 homolog
基因别名: AIBP63; BLOC2S2; HPS5; KIAA1017
UniProt ID: (Human) Q9UPZ3
Entrez Gene ID: (Human) 11234
