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Invitrogen
Hepatitis B Virus X Monoclonal Antibody (X36C)
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Hepatitis B Virus X Antibody (MA1-081) in WB
Oncology letters 2021 -
Figure 1. HBx increases NAMPT expression in liver cancer cells. (A) RT-qPCR and western blot analyses of NAMPT expression were performed in (A) HepG2 and HepG2.2.15 cells and (B) HepAD38 cells with or without Tet treatment. RT-qPCR and western blot analyses of NAMPT expression in (C) HepG2 and (D) Huh7 cells transfected with HBV1.3 or HBx plasmid. RT-qPCR and western blot analysis of NAMPT expression in (E)... View More
产品信息
MA1-081
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
已发表种属
C. elegans,
Virus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
X36C
抗原
Baculovirus expressed recombinant HBx.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
HPLC
保存液
PBS
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-081 detects hepatitis B x (HBx) protein from transfected human cells.
MA1-081 has been successfully used in Western blot, immunoprecipitation and ELISA procedures. By Western blot, this antibody detects a single ~17 kDa protein representing HBx. This antibody is not capable of immunoprecipitating HBx complexed with HBx interacting protein (XIP).
The MA1-081 immunogen is baculovirus expressed recombinant HBx.
靶标信息
The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The Hepatitis B X antigen is a 154 amino acid ~17 kDa multifunctional protein involved in the development of liver chirrosis and hepatocellular carcinoma. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
