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Hsp70/Hsc70 Monoclonal Antibody (BB70)

查看其他7个HSP70/HSC70抗体

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说明书
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产品信息

200-301-F64

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1 µg/mL
-

免疫组化（石蜡） (IHC (P))

Assay-dependent
-

免疫细胞化学 (ICC/IF)

Assay-dependent
-

免疫沉淀 (IP)

Assay-dependent
-
产品规格

种属反应

Bovine, Dog, Chicken, Fruit fly, Fish, Guinea pig, Hamster, Human, Mollusc, Mouse, Sheep, Pig, Rabbit, Rat, Whale, Xenopus, Yeast

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

BB70

抗原

Hsp70/Hsc70 Antibody was produced in mice by repeated immunizations raised against chicken Hsp70/Hsp90 complex.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

200 µg

纯化类型

Protein G

保存液

PBS, pH 7.2, with 50% glycerol

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

HSPA4 (Heat Shock Protein Family A (Hsp70) Member 4) is a Protein Coding gene. Diseases associated with HSPA4 include Chagas Disease and Babesiosis. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Cellular responses to stimuli. An important paralog of this gene is HSPH1. HSPA8 (Heat Shock Protein Family A (Hsp70) Member 8) is a Protein Coding gene. Diseases associated with HSPA8 include Auditory System Disease and Borna Disease. Among its related pathways are Processing of Capped Intron-Containing Pre-mRNA and Selective autophagy. Gene Ontology (GO) annotations related to this gene include RNA binding and ubiquitin protein ligase binding. An important paralog of this gene is HSPA2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Heat shock 70 kDa protein 1; Heat shock 70 kDa protein 4; Heat shock 70 kDa protein 8; Heat shock 70-related protein APG-2; heat shock 70kd protein 10 (HSC71); heat shock 70kD protein 8; heat shock 70kDa protein 1-like; heat shock 70kDa protein 4; heat shock 70kDa protein 8; heat shock cognate 70; heat shock cognate 71 kD protein; Heat shock cognate 71 kDa protein; heat shock cognate hsc73; Heat shock cognate protein 70; heat shock protein 8; heat shock protein A8; heat shock protein Apg-2; heat shock protein cognate 70; Heat shock protein family A member 8; Heat shock protein family H member 2; heat shock protein, 110 kDa; Hsc70 ATPase; HSP70RY; HSPA4/HSPA8; Ischemia responsive 94 kDa protein; LAP-1; Lipopolysaccharide-associated protein 1; unnamed protein product

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基因别名: 2410008N15Rik; 70kDa; AI317151; APG-2; APG2; HSC70; hsc70.I; Hsc71; Hsc73; Hsp110; HSP70; Hsp70RY; HSP73; HSPA1; HSPA10; hspa1l; HSPA4; HSPA8; HSPH2; I79_004332; I79_022974; Irp94; mKIAA4025; XELAEV_18037286mg; xhsp70

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UniProt ID: (Dog) Q7YQC6, (Dog) Q2TFN9, (Bovine) P19120, (Chicken) O73885, (Rat) O88600, (Chinese hamster) P19378, (Rat) P63018, (Mouse) P63017

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Entrez Gene ID: (Dog) 403612, (Pig) 100524853, (Chicken) 416339, (Bovine) 536558, (Dog) 474680, (Sheep) 101122782, (Rabbit) 100338049, (Bovine) 281831, (Dog) 479406, (Sheep) 101112844, (Chicken) 395853, (Rabbit) 100348873, (Pig) 100511890, (Chinese hamster) 100764628, (Mouse) 15525, (Rat) 266759, (Guinea pig) 100735343, (Chinese hamster) 100689472, (Guinea pig) 100713849, (Rat) 24468, (Mouse) 15481, (Western clawed frog) 100037899, (Xenopus) 379760

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功能
protein binding ATP binding ATPase activity heat shock protein binding protein binding involved in protein folding unfolded protein binding misfolded protein binding clathrin-uncoating ATPase activity nucleotide binding RNA polymerase II transcription factor binding protein complex binding activating transcription factor binding G-protein coupled receptor binding receptor binding enzyme binding MHC class II protein complex binding ubiquitin protein ligase binding ATPase activity, coupled ADP binding poly(A) RNA binding C3HC4-type RING finger domain binding
参与通路
mRNA processing RNA splicing synaptic vesicle uncoating negative regulation of transcription, DNA-templated negative regulation of protein phosphorylation response to heat positive regulation of gene expression negative regulation of gene expression positive regulation of protein binding negative regulation of apoptotic process negative regulation of DNA binding protein import into mitochondrial outer membrane chaperone-mediated protein complex assembly negative regulation of cell death kidney development positive regulation of angiogenesis protein refolding positive regulation of microtubule nucleation regulation of mitotic spindle assembly transcription, DNA-templated protein folding positive regulation of mRNA splicing, via spliceosome chaperone mediated protein folding requiring cofactor regulation of cell cycle chaperone-mediated protein folding clathrin coat disassembly negative regulation of fibril organization regulation of transcription, DNA-templated ATP metabolic process response to unfolded protein gastrulation axo-dendritic transport embryo development ending in birth or egg hatching vesicle-mediated transport cellular response to unfolded protein embryonic organ development late endosomal microautophagy protein targeting to lysosome involved in chaperone-mediated autophagy chaperone-mediated protein transport involved in chaperone-mediated autophagy chaperone-mediated autophagy translocation complex disassembly slow axonal transport
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