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Invitrogen
IRF6 Polyclonal Antibody
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产品信息
PA5-40472
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human IRF6
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: IPVVARMIYE MFSGDFTRSF DSGSVRLQIS TPDIKDNIVA QLKQLYRILQ
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%
靶标信息
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Interferon regulatory factor 6; IRF-6
基因别名: IRF6; LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
UniProt ID: (Human) G0ZTL0
Entrez Gene ID: (Human) 3664
transcription, DNA-templated
cell cycle arrest
negative regulation of cell proliferation
keratinocyte differentiation
keratinocyte proliferation
positive regulation of transcription, DNA-templated
cell development
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
mammary gland epithelial cell differentiation
