Invitrogen

Integrin beta 7 Polyclonal Antibody

Name: Integrin beta 7 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-102971
Availability: InStock

查看其他26个Integrin beta 7抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

Integrin beta 7 Antibody in Western Blot (WB)

图: 1 / 1

Integrin beta 7 Antibody (PA5-102971) in WB

Western blot analysis of Integrin beta 7 in COLO205 cells lysate. Samples were incubated with Integrin beta 7 polyclonal antibody (Product # PA5-102971).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image Integrin beta 7 Polyclonal Antibody

产品信息

PA5-102971

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human ITGB7(Accession P26010), corresponding to amino acid residues P504-S554.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2852345

产品详细信息

Antibody detects endogenous levels of total ITGB7.

靶标信息

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

仅用于科研。不用于诊断过程。未经明确授权不得转售。