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Invitrogen
JMJD5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100205
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KDM8(Accession Q8N371), corresponding to amino acid residues I291-Y341.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total KDM8.
Target Information
This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: arginyl C3-hydroxylase KDM8; JmjC arginyl-hydroxylase; jmjC domain-containing protein 5; jumonji C domain-containing protein 5; jumonji domain containing 5; jumonji domain-containing protein 5; L-arginine (3R)-hydroxylase KDM8; lysine (K)-specific demethylase 8; lysine-specific demethylase 8; unnamed protein product
Gene Aliases: 3110005O21Rik; JMJD5; RGD1304823
UniProt ID: (Human) Q8N371, (Mouse) Q9CXT6, (Rat) Q497B8
Entrez Gene ID: (Human) 79831, (Mouse) 77035, (Rat) 308976
G2/M transition of mitotic cell cycle
in utero embryonic development
chromatin remodeling
regulation of gene expression
protein destabilization
circadian regulation of gene expression
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
fibroblast proliferation
regulation of signal transduction by p53 class mediator
biological_process
peptidyl-arginine hydroxylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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