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Invitrogen
KCNT1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99644
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KCNT1(Accession Q5JUK3), corresponding to amino acid residues I1019-G1069.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total KCNT1.
靶标信息
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KCa4.1; KCa4.1KIAA1422FLJ41282; KNa1.1; Potassium channel subfamily T member 1; potassium channel subunit (Slack); potassium channel, subfamily T, member 1; Sequence like a calcium-activated potassium channel subunit; Slo2.2; Sodium and chloride-activated ATP-sensitive potassium channel Slo2.2
基因别名: C030030G16Rik; KCNT1; KIAA1422; rSlo2; SLACK; slo2; Slo2.2
UniProt ID: (Mouse) Q6ZPR4, (Rat) Q9Z258
Entrez Gene ID: (Mouse) 227632, (Rat) 60444
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