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Abnova
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRMEAGEAAP PAGAGGRAAG GWGKWVRLNV GGTVFLTTRQ TLCREQKSFL SRLCQGEELQ SDRDETGAYL IDRDPTYFGP ILNFLRHGKL VLDKDMAEEG VLEEAEFYNI GPLIRIIKDR MEEKDYTVTQ VPPKHVYRVL QCQEEELTQM VSTMSDGWRF EQLVNIGSSY NYGSEDQAEF LCVVSKELHS TPNGLSSESS RKTKSTEEQL EEQQQQEEEV EEVEVEQVQV EADAQEKGSR PHPLRPEAEL AVRASPRPLA RPQSCHPCCY KPEAPGCEAP DHLQGLGVPI
Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).
仅用于科研。不用于诊断过程。未经明确授权不得转售。